The Midwest is officially made up of 12 states - Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, and Wisconsin. While the landscape is mostly flat, largely made up of the Interior Plains, some variation in terrain can be found in the form of the Appalachian foothills, the Great Lakes Basin, and the Ozark Mountains. The northernmost states share a border with Canada, which is also where four of the five Great Lakes can be found - Lake Superior, Lake Michigan, Lake Huron, and Lake Erie. Big Midwest cities include Chicago, which is the most populated in the Midwest and the third most populated in the United States, Columbus, Cincinnati, St. Louis, and Des Moines. On the whole, the Midwest is a great place to get back to nature and take a break. What are you waiting for - check out these amazing dog-friendly vacation rentals in the Midwest!